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Advances in Cell Surface Shellization
Author NameAffiliationE-mail
SU Hui Department of Biomedical Engineering, Research Center for Nano-biomaterials & Regenerative Medicine, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China  
XU Hao Department of Biomedical Engineering, Research Center for Nano-biomaterials & Regenerative Medicine, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China  
ZHANG Li-Chuang Department of Biomedical Engineering, Research Center for Nano-biomaterials & Regenerative Medicine, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China  
XU Shuang-Meng Department of Biomedical Engineering, Research Center for Nano-biomaterials & Regenerative Medicine, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China  
WEI Yan Department of Biomedical Engineering, Research Center for Nano-biomaterials & Regenerative Medicine, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China
Shanxi Key Laboratory of Material Strength & Structural Impact, Institute of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China 
weiyan@tyut.edu.cn 
DU Jing-Jing Department of Biomedical Engineering, Research Center for Nano-biomaterials & Regenerative Medicine, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China
Shanxi Key Laboratory of Material Strength & Structural Impact, Institute of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China 
 
HUANG Di Department of Biomedical Engineering, Research Center for Nano-biomaterials & Regenerative Medicine, College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China
Shanxi Key Laboratory of Material Strength & Structural Impact, Institute of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China 
 
Abstract: The cell surface shellization is a kind of technology that mainly modifying cell surface to form a complete and uniform organic, inorganic, metal nanoparticles or composite shell structure with physical, chemical and other technical methods. So the cells, which cannot be shellized themselves, can form a protective shell outside and even gain new features, leading to form a multi-functional cell. In recent years, this technology has been widely used in cell storage, cell transportation, cell sensors, cell chips, and cell therapy, and has developed rapidly. This paper synthesizes the current research, and introduces in detail the cell types that can be used for cell surface shellization, the methods of bio-surface shellization, and the application of engineering techniques of artificial cell shells in biomedical and energy environments.
Keywords: cell shellization  cell functionalization  biomaterials  cell therapy
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SU Hui,XU Hao,ZHANG Li-Chuang,XU Shuang-Meng,WEI Yan,DU Jing-Jing,HUANG Di.Advances in Cell Surface Shellization[J].Chinese Journal of Inorganic Chemistry,2019,35(10):1713-1727.
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Chinese Journal of Inorganic Chemistry