| Mn(TDCPP)Cl/NaOCl单加氧酶模拟体系催化丙烯环氧化反应 |
| PROPYLENE EPOXIDATION CATALYZED BY A MONO-OXYGENASE MODEL SYSTEM OF Mn(TIDCPP)Cl / NaOCl |
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| 摘要: 采用高位阻金属卟啉[Mn(TDCPP)Cl]与单氧给体NaOCl结合组成细胞色素P-450单加氧醉模拟体系,系统考察了反应条件如轴向配体、pH值变化对催化丙烯环氧化能力的影响.并对反应的动力学进行了研究. |
| 关键词: 单加氧酶 模拟 催化环氧化 |
| 基金项目: 国家自然科学基金 |
| Abstract: Higher preventing hindered metal porphyrin complexes of Mn(TDCPP)Cl, Fe(TDCPP)Cl were synthesized using Lindsey method. A model system for Cytochrome P-450 was constructed through Mn(TDCPP)Cl with sodium hypochlorite(NaOCl), propylene epoxidation catalyzed by this system was investigated.The results showing:1. Mn(TDCPP)Cl/ NaOCl is a good model system for Cytochrome P-450,with this system, higher catalytic activity and selectivity for propylene oxide formation can be obtained. The effects of axial ligands addition,PH value variation of NaOCl aqucous solution on the catalytic activity were also studied.2.The kinetic results indicated that:when the Mn(TDCPP)Cl concentration range in organic phase was at 0 to 3.5×10-4mol·l-1, the reaction order for Mn(TDCPP)Cl was 1 with the increase of Mn(TDCPP)Cl concentration;within the concentration range of NaOCl at 0 to 0.4mol·l-1.the reaction order variation for NaOCl was from 1 to 0;When the propylene concentration was changed. the initial velocity for propylene oxide formation was retained constant.3. When appropriate reaction condition was chosen with the cetylpyridinc bromide prescnted as the axial ligand,the turnover numbers of propylene oxide formation per minute reachto 3.8,the Mn(TDCPP)Cl retained stable after 24 hours reaction. |
| Keywords: mono-oxygenase catalytic epoxidation model |
| 投稿时间：1993-02-25 |
| 摘要点击次数: 1404 |
| 全文下载次数: 1591 |
| 索继栓,李树本,王弘立.Mn(TDCPP)Cl/NaOCl单加氧酶模拟体系催化丙烯环氧化反应[J].无机化学学报,1995,11(3):313-318. |
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