| 氨基酸、多肽的环糊精化学 |
| Cyclodextrin Chemistry on Amino Acids and Peptides |
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| 摘要: 本文着重介绍了氨基酸-、多肽-环糊精连接物的合成、分子识别和自组装,对环糊精及其衍生物与氨基酸、多肽的包合行为、异构体识别和仿酶合成作了简要概述。 |
| 关键词: 环糊精 氨基酸 多肽 包合物 分子识别 |
| 基金项目: 国家自然科学杰出青年基金资助项目(No.29925102) |
| Abstract: Many kinds of modified cyclodextrin s(CDs )bearing the functions such as cataly tic ac-tivity,membrane permeability and molecular recognition sensor,have b een synthesized and inves-tigated.In order to further realize a supramolecular recognition syste m and develop new functional mateials based on cyclodxtrins and a mino acids or peptides,we have desig ned and synthesized a series of CD-amino acid conjugates a nd investigated their affinity towa rds small peptide molecules.This paper summarized recent progre sses on the synthesis and molecular r ecognition of amino acid-or peptide-cyclodextrin conjugates a nd discussed the inclusion behaviou r or self-assembly of cyclodex-trins and their derivatives with som e guests such as amino acids or peptid es. |
| Keywords: cyclodextrin amino acid peptide inclusion compound molecular recognition |
| 投稿时间：2001-03-14 修订日期：2001-04-26 |
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| 宋乐新,郭子建.氨基酸、多肽的环糊精化学[J].无机化学学报,2001,17(4):457-470. |
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