| 荧光染料探针与脱氧核糖核酸作用机理研究 |
| Study on the Interaction Mechanism of Fluorescence Dyes with DNA |
|
| 摘要: 核酸与各类物质的相互作用与探测核酸的结构与功能密切相关是揭示核酸的生物功能和一些药物的作用机制的重要途径。本文研究了染料ZR、甲酚红、苏木色精等与DNA的作用给出它们在不同结合数下的生成常数。此外还求取了它们的能量转移效率、给体受体之间的距离。 |
| 关键词: 荧光染料 脱氧核糖核酸 给体与受体 |
| 基金项目: 国家自然科学基金资助项目 |
| Abstract: Interaction of nucleic acid with various substances is closely related t o detecting the structure and function of nucleic acid,which i s an important way of discovering bio logical function of nucleic acid and action mechanism of some dru gs.In this article,the interaction s of dye ZR,cresol red,and hematoxylin etc with DNAhave been studied,and the association constant with different binding numbers has also been obtained;Furthermore,we have also got the energy t ransferring efficiency and the distance of donor and accepto r. |
| Keywords: fluorescence dyes DNA don or and acceptor |
| 投稿时间：2001-04-17 修订日期：2001-06-21 |
| 摘要点击次数: 1438 |
| 全文下载次数: 2191 |
| 席小莉,杨曼曼,韩小见,杨频.荧光染料探针与脱氧核糖核酸作用机理研究[J].无机化学学报,2001,17(6):781-786. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| Support information: |
|
|
|
|
|
|
