LB膜诱导下草酸钙晶体的生物矿化研究
The Study on the Biomineralization of Calcium Oxalate Crystals Induced by LB Film
作者单位
钟玖平 暨南大学生物矿化与结石病防治研究所,广州 510632 
欧阳健明 暨南大学生物矿化与结石病防治研究所,广州 510632 
邓穗平 暨南大学生物矿化与结石病防治研究所,广州 510632 
摘要: 
关键词: 草酸钙晶体 LB膜 二棕榈酰磷脂酰胆碱 生物矿化
基金项目: 
Abstract: The effects of urinary macromolecule chondroitin sulfate A(C4S) and L-glutamic acid (L-Glu) on the crys-tallization of calcium oxalate were studied using Langmuir-Blodgett(LB) film of dipalmitoylphosphatidylcholine (DPPC) as templet. All the calcium oxalate crystals induced by the LB film of DPPC were calcium oxalate monohydrate(COM). However, the morphology of COM was influenced by the additives of C4S and L-Glu. C4S induced thin and long hexagonal COM crystals; L-Glu made one or two (010) crystal face of COM crystals dis-appeared. The crystallization time had no effect on the morphology of COM crystals, but the concentration of C4S and L-Glu changed it. As increasing the concentration of C4S, the amount of COM crystals with a hexagonal prism decreased and that with a thin hexagonal slice increased. When the concentration of C4S was 0.50mg·mL-1, all the calcium oxalate crystals were thin hexagonal slice COM crystals. However, as the concentration of L-Glu in-creased from 0.01 to 0.50mmol·L-1, the hexagonal prism-like COM crystals gradually transformed to COM crystals with one or two (010) crystal face disappearance.
Keywords: calcium oxalate crystal LB film dipalmitoylphosphatidylcholine biomineralization
 
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钟玖平,欧阳健明,邓穗平.LB膜诱导下草酸钙晶体的生物矿化研究[J].无机化学学报,2002,18(12):1253-1257.
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