| 双(4，5-二氮杂芴酮)缩对，对′-二氨基二苯甲烷桥联的二(邻菲咯啉合铜(Ⅱ))的合成及其与DNA作用的光谱研究 |
| Synthesis and Spectroscopic DNA Binding Studies of 1，1′-Bis(nitrilomethylidyne-4，5-diazafluoren)-4，4′-(μ-methylene)bisphenyl Bridged Bis(1，10-phenanthrolinocopper(Ⅱ)) Complex |
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| 摘要: |
| 关键词: Cu(Ⅱ)双核配合物 邻菲咯啉 小牛胸腺DNA 双-(4，5-二氮杂芴酮)缩对，对′-二氨基二苯甲烷 |
| 基金项目: |
| Abstract: A new bimetallic Cu(Ⅱ) complex， [(phen)Cu(μ-bdmp)Cu(phen)](ClO4)4·2H2O， where phen and bdmp denote 1，10-phenanthroline and 1，1′-bis(nitrilomethylidyne-4，5-diazafluoren)-4，4′-(μ-methylene)bisphenyl re-spectively was synthesized and its DNA binding behavior was studied by photophysical methods. It has been found that calf thymus DNA could result in significant decrease both in electronic absorption and fluorescent emission of the complex. The fluorescence quenching by ferrocyanide could be reduced to some extent for the complex in presence of DNA. These facts suggest that this dicopper(Ⅱ) complex binds to double helix DNA by partial inter-calation. |
| Keywords: dinuclear copper(Ⅱ) complex 1,10-phenanthroline calf thymus DNA 1,1′-bis(nitrilomethylidyne-4,5-diazafluoren)-4,4′-(μ-methylene)bisphenyl |
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| 钟文添,吴建中.双(4，5-二氮杂芴酮)缩对，对′-二氨基二苯甲烷桥联的二(邻菲咯啉合铜(Ⅱ))的合成及其与DNA作用的光谱研究[J].无机化学学报,2003,19(2):196-200. |
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