二胺桥联邻菲罗啉衍生物的合成及其与DNA相互作用研究 |
Synthesis and DNA Binding Studies of Diamine-bridged 1,10-phenanthroline Derivatives |
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摘要: |
关键词: 邻菲罗啉 DNA La(Ⅲ)配合物 |
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Abstract: A new ligand N,N′-bis(2-methelene-1,10-phenanthroline)-3,6-dioxa-1,8-octaneethylenediamine(L) and the corresponding complexes LaL, LaL(Phe), and LaL(Try) were synthesized. The interaction of the complexes with calf thymus DNA was studied by means of electronic absorbance spectra, flurescence spectra, circular dichroic spectra and viscosity experiments. All the results indicate that the complexes may interact mainly with calf thymus DNA by intercalation and coordination binding. |
Keywords: o-phenanthroline DNA La(Ⅲ) complex |
投稿时间:2004-05-24 修订日期:2004-08-12 |
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吴红星,李风华,林海,林华宽.二胺桥联邻菲罗啉衍生物的合成及其与DNA相互作用研究[J].无机化学学报,2005,21(1):117-122. |
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