二胺桥联邻菲罗啉衍生物的合成及其与DNA相互作用研究
Synthesis and DNA Binding Studies of Diamine-bridged 1,10-phenanthroline Derivatives
作者单位
吴红星 南开大学化学系天津 300071 
李风华 南开大学化学系天津 300071 
林海 南开大学吸附分离功能高分子材料国家重点实验室天津 300071 
林华宽 南开大学化学系天津 300071 
摘要: 
关键词: 邻菲罗啉  DNA  La(Ⅲ)配合物
基金项目: 
Abstract: A new ligand N,N′-bis(2-methelene-1,10-phenanthroline)-3,6-dioxa-1,8-octaneethylenediamine(L) and the corresponding complexes LaL, LaL(Phe), and LaL(Try) were synthesized. The interaction of the complexes with calf thymus DNA was studied by means of electronic absorbance spectra, flurescence spectra, circular dichroic spectra and viscosity experiments. All the results indicate that the complexes may interact mainly with calf thymus DNA by intercalation and coordination binding.
Keywords: o-phenanthroline  DNA  La(Ⅲ) complex
投稿时间:2004-05-24 修订日期:2004-08-12
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吴红星,李风华,林海,林华宽.二胺桥联邻菲罗啉衍生物的合成及其与DNA相互作用研究[J].无机化学学报,2005,21(1):117-122.
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