| 5-氟尿嘧啶-1-乙酸合铜(Ⅱ)的合成及其与DNA的作用 |
| The Interactions between 5-fluorouracil-1-acetic Acid and its Capper(Ⅱ) Complex with DNA |
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| 摘要: |
| 关键词: 5-氟尿嘧啶-1-乙酸合铜(Ⅱ) DNA 静电吸附 |
| 基金项目: |
| Abstract: The 5-fluorouracil-1-acetic acid (5FuAA) and its Cu(Ⅱ) complex (5FuAACu) were synthesized and the date for the crystal complex was obtained. The interaction of 5-fluorouracil-1-acetic acid (5FuAA) and its Cu(Ⅱ) complex (5FuAACu) with DNA was also investigated by using spectral, viscometric, electrochemical and agarose gel electrophoresis methods. The results of interaction with DNA suggest that both 5FuAA and 5FuAACu can bind to DNA in a static electricity attraction mode. But the attraction of 5FuAACu is greater than that of 5FuAA. |
| Keywords: 5FuAACu DNA static attraction |
| 投稿时间：2005-02-22 修订日期：2005-05-09 |
| 摘要点击次数: 1057 |
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| 王志平,张强,宋玉民,黄键,王流芳.5-氟尿嘧啶-1-乙酸合铜(Ⅱ)的合成及其与DNA的作用[J].无机化学学报,2005,21(9):1397-1401. |
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