| 叶酸受体靶向CdS量子点应用于HepG2细胞成像研究 | |
| Folate-receptor Targeted CdS Quantum Dots for Identifying Tumor Cell HepG2 | |
| 摘要: | |
| 关键词: 量子点 表面修饰 细胞靶向 叶酸受体 生物成像 | |
| 基金项目: | |
| Abstract: High quality CdS quantum dots (CdS QDs) with a narrow size distribution have been synthesized through a reverse micelle route. Chemical modification and folate-functionalization of the QDs resulted in the bio-targeted fluorescent quantum dots(QDFs). Transmission electron microscopy (TEM) and photoluminescence emission spectroscopy were employed to characterize the morphologies and the optical properties of the QDs. Observation on the incorporation of QDFs with tumor cells (HepG2) under laser confocal fluorescent microscopy indicated that the QDFs could successfully identify the target tumor cells with high expression levels of folate receptor. | |
| Keywords: quantum dots (QDs) surface modification cell-targeted folate-receptor bio-imaging | |
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| 张培根,余德才,程传伟,贺志鹏,张晓红,力虎林,张海黔.叶酸受体靶向CdS量子点应用于HepG2细胞成像研究[J].无机化学学报,2007,23(9):1662-1666. | |
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