乌梅提取液对草酸钙晶体生长的抑制作用研究
Inhibitory Effect of Extract from Fuctus Mume on Calcium Oxalate Crystal Growth
作者单位
王 萍 安徽大学化学化工学院合肥 230039
安徽省中医学院药学院合肥 230031 
沈玉华 安徽大学化学化工学院合肥 230039 
谢安建 安徽大学化学化工学院合肥 230039 
李士阔 安徽大学化学化工学院合肥 230039 
黄方志 安徽大学化学化工学院合肥 230039 
裘灵光 安徽大学化学化工学院合肥 230039 
摘要: 本文研究了水体系中加入乌梅提取液对草酸钙晶体生长的抑制作用,通过FTIR、SEM及XRD等测试方法对所得晶体进行表征。结果表明,不加乌梅提取液的体系中形成的晶体为一水合草酸钙(COM)晶体,加入乌梅提取液后,形成的是二水合草酸钙(COD)晶体,而且COD晶体的尺寸随着乌梅提取液浓度的增大而减小,直至消失,这说明乌梅提取液具有抑制草酸钙晶体生长的作用,且这种抑制作用随乌梅浓度的增大而增大。本文还通过电导率法研究了草酸钙晶体生长的动力学过程,发现乌梅提取液主要能抑制草酸钙晶体的成核过程。
关键词: 草酸钙  泌尿结石  乌梅  抑制  电导率
基金项目: 
Abstract: The inhibitory effect of the extract from Fuctus Mume on the crystallization of calcium oxalate crystals in aqueous solution was studied, and the crystals were characterized by Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), and scanning electron microscopy (SEM). The results showed that the calcium oxalate monohydrate (COM) was the dominant phase in pure water while calcium oxalate dehydrate (COD) crystal alone appeared in the extract of Fuctus Mume. The size of the COD crystals reduced apparently as the content of the extract of Fuctus Mume increased in water. It suggests that the extract of Fuctus Mume could inhibit the crystallization of calcium oxalate monohydrate, and the inhibiting ability increases along with the increase of the extract concentration. The kinetic growth process of calcium oxalate crystals was studied by monitoring the electrical conductivity of solution and the result suggests that the extract of Fuctus Mume mainly inhibits the nucleation of CaC2O4.
Keywords: calcium oxalate  urinary stone  fuctus mume  prohibition  electrical conductivity
 
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王 萍,沈玉华,谢安建,李士阔,黄方志,裘灵光.乌梅提取液对草酸钙晶体生长的抑制作用研究[J].无机化学学报,2008,24(10):1604-1609.
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