| Abstract: A new ruthenium(Ⅱ) complex containing aliphatic polyamine [Ru(dipn)(tpy)](ClO4)2(1), (tpy and dipn stand for 2,2′∶6′2″-terpyridine and N-(3-aminopropyl)propane-1,3-diamine, respectively) was synthesized and charac-terized by EA, ESMS, UV-Vis and CV. The DNA-binding behaviors of this complex were studied by absorption titration, EB-competition fluorescence spectra and viscosity measurements, compared with those of it′s series compounds [Ru(dipn)(dptp)](ClO4)2(2) and [Ru(dipn)(pat)](ClO4)2(3) (dptp=2-(5,6-diphenyl-1,2,4-triazin-3-yl)-1,10-phenanthroline; pat=9-(1,10-Phenanthrolin-2-yl) acenaphtho[1,2-e][1,2,4]triazine). The results indicate that the three complexes interact with DNA in different mode: electrostatic attraction, partial intercalation and intercalation for 1, 2 and 3, respectively. Their DNA affinities are in order: 1 < 2 < 3. |
