| 氧化-4-吡啶甲酸桥联的一维链状三丁基锡配合物的合成与晶体结构(英文) |
| Synthesis and Crystal Structure of the One-Dimensional Chain Tributyltin Compound Bridged by Pyridine-4-carboxylic Acid N-Oxide |
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| 摘要: 利用双三丁基氧化锡与氧化-4-吡啶甲酸(HOCOC5H4NO)以物质的量比1∶2反应，合成了有机锡配合物[Bu3Sn(OCOC5H4NO)]n。通过元素分析、红外光谱和核磁共振氢谱对其结构进行了表征，用X射线单晶衍射测定了它的晶体结构。结果表明，该配合物晶体属单斜晶系，空间群为C2/c, 晶胞参数a=2.002 8(9) nm，b=1.224 7(6) nm，c=1.913 6(12) nm，β=119.145(6)°，Z=8，V=4.166(4) nm3，Dc=1.365 g·cm-3，μ=1.239 mm-1，F(000)=1 760，R=0.052 9，wR=0.192 1，GOF=1.013。在配合物中锡原子由氧化-4-吡啶甲酸桥联为五配位的畸变的三角双锥构型。氧化-4-吡啶甲酸配体中N-O基团中的氧原子和另一配体中的羧基氧原子与中心锡原子配位，形成无限一维链状有机锡配合物。该配合物具有良好的热稳定性和较高的抗肿瘤活性。 |
| 关键词: 有机锡配合物 氧化-4-吡啶甲酸 合成 晶体结构 |
| 基金项目: |
| Abstract: An organotin compound [Bu3Sn(OCOC5H4NO)]n has been synthesized by the reaction of bistributyltin oxide with pyridine-4-carboxylic acid N-oxide (HOCOC5H4NO) in molar ratio of 1∶2 and characterized by elemental analysis, IR and 1H NMR. The crystal structure has been determined by X-ray single crystal diffraction. The crystal belongs to monoclinic space group C2/c, with a=2.002 8(9) nm, b=1.224 7(6) nm, c=1.913 6(12) nm, β=119.145(6)°, Z=8, V=4.166(4) nm3, Dc=1.365 g·cm-3, μ=1.239 mm-1, F(000)=1 760, R=0.052 9, wR=0.192 1, GOF =1.013. In the compound, tin atoms are five-coordinated distorted trigonal bipyramid configuration with bridging pyridine-4-carboxylic acid N-oxide. A one-dimensional linear polymer is formed through an interaction between the central tin atom and two O atoms. One O atom is from N-O and the other is from carboxyl group of another ligand. The compound exhibits good thermal stability and high antitumor activity. CCDC: 821908. |
| Keywords: organotin compound pyridine-4-carboxylic acid N-oxide synthesis crystal structure |
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| 高中军,刘广军,赵广旺.氧化-4-吡啶甲酸桥联的一维链状三丁基锡配合物的合成与晶体结构(英文)[J].无机化学学报,2012,28(2):386-390. |
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