| 含苯并咪唑基配体的锌配合物的晶体结构和催化对硝基苯磷酸酯水解的活性研究(英文) |
| Crystal Structure of Zinc(Ⅱ) Complex Containing Benzimidazole and Its Catalytic Activity of Hydrolysis of p-Nitrophenyl Phosphate |
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| 摘要: 合成和表征了一种磷酸脂酶模型化合物[Zn(L1)(L2)]·H2O(L1=二(2-苯并咪唑亚甲基)胺，L2=5-二甲基萘胺-1-磺酰甘氨酸)，并用对硝基苯磷酸酯(PNPP)作为反应底物测试了它的催化活性。研究结果表明锌配合物为扭曲的三角双锥构型，它催化PNPP的水解符合米氏方程模型。在不同的条件下测试了几种反应动力学参数Vmax、Km和kcat，发现锌配合物在35 ℃和pH=8.5时有最大的催化活性。 |
| 关键词: 锌 苯并咪唑 晶体结构 催化活性 |
| 基金项目: |
| Abstract: A phosphoester model complex [Zn(L1)(L2)]·H2O was synthesized and characterized (L1=bis(benzimidazol -2-yl-methyl)amine, L2=5-dimethylaminonaphthalene-1-sulphonylglycine), and its catalytic activity was investigated by using p-nitrophenyl phosphate (PNPP) as the substrate. The results showed that the zinc complex exhibit distorted trigonal-bipyramidal geometry, its catalytic hydrolysis of PNPP was consistent with Michaelis-Mentent model. Several kinetic parameters Vmax, Km and kcat were examined under different conditions, and maximal catalytic activity was observed at a temperature of 35 ℃ and pH=8.5. CCDC: 867155. |
| Keywords: zinc benzimidazole crystal structure catalytic activity |
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| 张 勇,舒威虎,王继猛,马志刚,陈雪梅.含苯并咪唑基配体的锌配合物的晶体结构和催化对硝基苯磷酸酯水解的活性研究(英文)[J].无机化学学报,2013,29(2):419-423. |
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