| 三(2-羟基-苯甲醛)乙醇胺三足配体汞(Hg)配合物的合成、结构及其与DNA相互作用的研究 | |
| Synthesis, DNA-Bonding Properties Study of Mercury(Ⅱ) Complex with Tris[(p-hydroxybenzaldehyde) ethyl]amine | |
| 摘要: 合成了基于邻羟基苯甲醛的三足配体Tris[(p-hydroxybenzaldehyde)ethyl]amine(L)，得到了该配体与汞的配合物，应用单晶X射线衍射技术测定了配体及其汞配合物的结构；应用用紫外吸收光谱、荧光光谱和粘度测定研究该配合物与小牛胸腺DNA的作用。结果表明，该配合物与小牛胸腺DNA以插入的方式相结合。 | |
| 关键词: 三足配体汞配合物 小牛胸腺DNA 插入作用 | |
| 基金项目: | |
| Abstract: Mercury(Ⅱ) complex with tris [(p-hydroxybenzaldehyde)ethyl]amine has been synthesized and characterized. The crystal and molecular structures of the complex was determined by singlecrystal X-ray diffraction. The interaction of complex with calf thymus DNA was investigated by UV-Vis、fluorescence spectrum and viscosity measurements. Results suggest that complex can bind to DNA via intercalation mode. CCDC: 952313, L; 843072, complex. | |
| Keywords: tripodal ligand mercury(Ⅱ) complex calf thymus DNA intercalation mode | |
| 投稿时间：2013-12-16 修订日期：2013-06-19 | |
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| 陈凤娟,朱永泽,朱锐伦,刘国旗,马骞,李洁,彭万通,陈国举,曾正志.三(2-羟基-苯甲醛)乙醇胺三足配体汞(Hg)配合物的合成、结构及其与DNA相互作用的研究[J].无机化学学报,2013,29(12):2561-2567. | |
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