| 含吡啶的大环席夫碱锰(Ⅱ)配合物：合成、表征及抗菌性质 |
| Manganese(Ⅱ) Macrocyclic Schiff-Base Complexes Containing Pyridine Moiety: Synthesis and Characterization and Antibacterial Properties |
| 作者 | 单位 | E-mail | | Keypour Hassan | Faculty of Chemistry, Bu-Ali Sina University, Hamedan 65174, Iran | haskey1@yahoo.com | | Liyaghati-Delshad Mozhdeh | Faculty of Chemistry, Bu-Ali Sina University, Hamedan 65174, Iran | | | Rezaeivala Majid | Department of Chemical Engineering, Hamedan University of Technology, Hamedan 65155, Iran | mrezaeivala@hut.ac.ir,mrezaeivala@gmail.com | | Khavasi Hamid Reza | Department of Chemistry, Shahid Beheshti University, G.C., Evin, Tehran 1983963113, Iran | |
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| 摘要: 在Mn（Ⅱ）模板作用下，2，6-diacetylpyridine（DAP）及合适链状胺化合物通过[1+1]环缩合反应，合成了3个大环席夫碱配合物，并进行了红外、元素分析、质谱及电导率等表征及研究。测得了配合物[MnL1（CH3CN）]（ClO4）2的晶体结构，中心离子呈现出稍微扭曲的五角锥配位构型。研究了配合物对S. aureus（ATCC 6633），B. cereus（ATCC 7064），C. xerosis（ATCC 373）（gram-positive bacterial strains），E. coli（PTCC 10009），K. pneuomoniae（MTCC 109），and P. vulgaris（lio）（gram-negative bacterial strains）的抗菌活性。结果显示[MnL3]（ClO4）2抗菌活性明显优于[MnL1（CH3CN）]（ClO4）2 and [MnL2]（ClO4）2.在25 ℃条件下0.1 mol·L-1 KCl溶液中，通过电位计量法测定了化合物的质子化常数。 |
| 关键词: 大环配体 席夫碱 锰(Ⅱ)配合物 抗菌活性 质子化常数 |
| 基金项目: |
| Abstract: Three new macrocyclic Schiff-base complexes have been prepared via the Mn(Ⅱ) templated [1+1] cyclocondensation of 2,6-diacetylpyridine (DAP) and appropriate linear amines. All complexes were characterized by IR spectra, elemental analysis, EI-Mass and conductivity measurements. The crystal structure of [MnL1(CH3CN)](ClO4)2 is also reported and exhibits a slightly distorted pentagonal-pyramidal geometry. Also the synthesized complexes were screened for their antibacterial activity against S. aureus (ATCC 6633), B. cereus (ATCC 7064), C. xerosis (ATCC 373) (gram-positive bacterial strains), E. coli (PTCC 10009), K. pneuomoniae (MTCC 109), and P. vulgaris (lio) (gram-negative bacterial strains). The results show that the antibacterial activity of [MnL3](ClO4)2 is greater than that of [MnL1(CH3CN)](ClO4)2 and [MnL2](ClO4)2. The protonation constants of three tetraamines have been determined potentiometrically in 0.1 mol·L-1 KCl at 25 ℃. CCDC: 964534. |
| Keywords: macrocyclic ligand Schiff base manganese(Ⅱ) complex antibacterial effect protonation constant |
| 投稿时间：2013-12-13 修订日期：2014-03-19 |
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| Keypour Hassan,Liyaghati-Delshad Mozhdeh,Rezaeivala Majid,Khavasi Hamid Reza.含吡啶的大环席夫碱锰(Ⅱ)配合物：合成、表征及抗菌性质[J].无机化学学报,2014,30(7):1733-1740. |
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