| 三维锌配位聚合物的合成、晶体结构及与DNA的作用 | |
| A Series of Zinc Polymer with 3D Construction: Syntheses, Structures and DNA-Binding | |
| 摘要: 在水热条件下,由联苯-2,4,4',6-四甲酸(H4bptc),4,4'-联吡啶(bipy),合成了3种锌配位聚合物[Zn(bptc)0.5]n(1),[Zn2(bptc)(H2O)3]n·nH2O(2),[Zn2(bptc)(H2O)(bipy)1.5]n·nH2O(3),用元素分析、红外光谱等方法对配合物的组成进行了表征,并通过单晶X-射线衍射方法测定了配合物的晶体结构.结果表明:配合物1具有双核结构,八元环金属簇Zn2(COO)22+自组装成具有(6,6)-连接拓扑结构;配合物2具有(4,5,6)-连接拓扑结构;配合物3在辅助配体的构筑下形成三维网络结构.用溴化乙锭荧光探针法测试了配合物对EB-DNA复合体系的荧光猝灭效应,实验结果显示配合物均能使EB-DNA复合体系的荧光发生不同程度的猝灭,由此推测配合物均与DNA发生了不同程度的插入作用,引入具有刚性平面辅助配体之后的配合物3,其作用力又强于不加辅助配体的配合物1和2. | |
| 关键词: 联苯-2,4,4',6-四甲酸 锌配位聚合物 DNA作用 | |
| 基金项目: 浙江省自然科学基金(No.LY12B01003)资助项目 | |
| Abstract: Three zinc complexes [Zn(bptc)0.5]n (1), [Zn2(bptc)(H2O)3]n·nH2O (2), [Zn2(bptc)(H2O)(bipy)1.5]n·nH2O (3), were synthesized under hydrothermal reactions by using biphenyl-2,4,4',6-tetracarboxylic acid (H4bptc) and 4,4'-Bipyridine (bipy). They were characterized by elemental analysis, IR spectra. Crystal structures of the complexes were determined by single crystal X-ray diffraction method. Complex 1 is binuclear structure, eight ring metal clusters with (4,4) topology. Complex 2 is a (4,5,6) topology construction. Complex 3 is a 3D network structure formed by ligand and auxiliary ligand. The interaction between three complexes and DNA were studied by EtBr fluorescence probe. Add the rigid auxiliary ligand, the interaction of complex 3 to the DNA is stronger than complex 1 and 2. CCDC: 952957, 1; 952958, 2; 952959, 3. | |
| Keywords: biphenyl-2,4,4',6-tetracarboxylic acid zinc polymer DNA-binding | |
| 投稿时间：2014-05-07 修订日期：2014-09-09 | |
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| 石沛,沈伟,余玉叶,吴小勇,赵国良.三维锌配位聚合物的合成、晶体结构及与DNA的作用[J].无机化学学报,2015,31(1):45-53. | |
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