| 咪唑-菲咯啉-苯氧乙酸锌、铅配合物的合成,结构及与DNA的相互作用 |
| Syntheses, Structures and DNA Interaction of Zn(Ⅱ) and Pb(Ⅱ) Complexes Based on Imidazo-phenanthrolin-phenoxy Acetic Acid |
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| 摘要: 以2-4-(1H-咪唑-2-[4,5-f][1,10]菲咯啉基)苯氧乙酸(HPIMPHC)和2-2-(1H-咪唑-2-[4,5-f][1,10]菲咯啉基)苯氧乙酸(HOIMPHC)为配体,水热合成了2种新型配合物[Zn(PIMPHC)2]n(1)和{[Pb(OIMPHC)2]·4H2O}n(2)。配合物1属正交晶系,空间群为Pbcn;Zn(Ⅱ)的配位数为6,配位构型为变形的八面体,形成2D网状结构。配合物2属单斜晶系,空间群为P21/n;Pb(Ⅱ)的配位数为7,配位构型为变形的五角双锥,形成2D网状结构。荧光光谱的结果表明,配合物与DNA的相互作用强于配体。 |
| 关键词: 2-4-(1H-咪唑-2-[4,5-f][1,10]菲咯啉基)苯氧乙酸 2-2-(1H-咪唑-2-[4,5-f][1,10]菲咯啉基)苯氧乙酸 Zn(Ⅱ) Pb(Ⅱ) DNA作用 |
| 基金项目: 浙江省自然科学基金(No.LY12B01003)资助项目。 |
| Abstract: Two novel complexes [Zn(PIMPHC)2]n(1), {[Pb(OIMPHC)2]·4H2O}n(2) were synthesized under hydro-thermal reactions by using2-(4-(1H-imidazo-2-[4,5-f][1,10]phenanthrolinyl)phenoxy) acetic acid (HPIMPHC) and 2-(2-(1H-imidazo-2-[4,5-f][1,10]phenanthrolinyl)phenoxy) acetic acid (HOIMPHC). Complex 1 crystallizes in orthorhombic system with space group Pbcn. Zn(Ⅱ) is six-coordinated by two PIMPHC-anions, forming a distorted octahedral coordination geometry. Complex 2 crystallizes in monoclinic system with space group P21/n, Pb(Ⅱ) is seven-coordinated, forming a distorted pentagonal bipyramid coordination geometry. The fluorescence spectra indicate that the interaction of the complexes with DNAare stronger than ligands. |
| Keywords: 2-(4-(1H-imidazo-2-[4,5-f][1,10]phenanthrolinyl)phenoxy) acetic acid 2-(2-(1H-imidazo-2-[4,5-f][1,10]phenanthrolinyl) phenoxy) acetic acid Zn(Ⅱ) Pb(Ⅱ) DNA-binding |
| 投稿时间：2016-01-17 修订日期：2016-04-23 |
| 摘要点击次数: 1932 |
| 全文下载次数: 1194 |
| 沈伟,胡未极,吴小勇,赵国良.咪唑-菲咯啉-苯氧乙酸锌、铅配合物的合成,结构及与DNA的相互作用[J].无机化学学报,2016,32(6):1101-1110. |
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