两个基于苯并咪唑席夫碱的镍(Ⅱ)配合物的合成、晶体结构和抑菌活性
Two Ni(Ⅱ) Complexes of Schiff Base Ligands Containing Benzimidazole Ring: Syntheses, Crystal Structures and Antibacterial Properties
作者单位E-mail
赵海燕 河北科技大学理学院, 石家庄 050018 hbhaiyanzh@163.com 
杨晓东 河北科技大学理学院, 石家庄 050018  
李娜 河北科技大学理学院, 石家庄 050018  
摘要: 在甲醇体系中,分别将苯并咪唑席夫碱HL1和HL2与高氯酸镍进行配位反应得到2个结构类似的镍配合物[Ni(L12]·2H2O(1)和[Ni(L22]·2H2O(2)(HL1=N-(benzimidazol-2-ylethyl)-5-chlorosalicylideneimine,HL2=N-(Benzimidazol-2-ylethyl)-5-bromosalicyli-denei-mine),并用元素分析、红外光谱、紫外-可见光谱和单晶X射线衍射对其结构进行了表征。结构分析表明:两个配合物均属于单斜晶系,C2/c空间群,Ni(Ⅱ)与来自2个席夫碱配体的4个氮原子和2个氧原子配位,形成八面体结构。配合物中的氢键将配合物1和配合物2分别连接成二维和三维网络结构。选取金黄色葡萄球菌和大肠杆菌作为菌种,研究了2个席夫碱配体和2个配合物的抑菌能力。
关键词: 席夫碱  镍(Ⅱ)配合物  晶体结构  抑菌活性
基金项目: 2015年河北科技大学五大平台开放基金课题(No.50)资助。
Abstract: Two complexes[Ni(L1)2]·2H2O (1) and[Ni(L2)2]·2H2O (2) have been synthesized using the bezimidazole derived tridentate (NNO donor) potential Schiff base ligands HL1 and HL2, which are prepared from reaction of 2-aminoethyl-1H-benzimidazole with 5-chlorosalicylaldehyde and 5-bromosalicylaldehyde, respectively, and characterized by elemental analysis, FT-IR and UV-Vis spectroscopies and single crystal X-ray crystallography. In 1 and 2, each Ni(Ⅱ) has a distorted octahedral arrangement with a N4O2 donor set in trichelated fashion of the Schiff base ligands. Furthermore, the complex units in 1 and 2 are linked into 2D and 3D supramolecular networks by H-bonding in the solid state, respectively. The bioactivity studies showed that both the two complexes exhibit moderate to strong antibacterial activities against S. aureus (Gram-positive) and E. coli (Gram-negative) bacteria and were found more active than the corresponding Schiff base ligands.
Keywords: Schiff base  Ni(Ⅱ) complex  crystal structure  antibacterial activity
投稿时间:2016-11-07 最后修改时间:2017-02-04
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赵海燕,杨晓东,李娜.两个基于苯并咪唑席夫碱的镍(Ⅱ)配合物的合成、晶体结构和抑菌活性[J].无机化学学报,2017,33(4):685-691.
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