| 2-氨基吡啶类双核铜(Ⅱ)配合物的合成、晶体结构及性质 | |
| Syntheses, Crystal Structures, and Properties of Binuclear Copper(Ⅱ) Complexes Derived from 2-Aminopyridines | |
| 摘要: 分别以3-甲基-2-氨基吡啶(L1)、5-溴-2-氨基吡啶(L2)为配体，采用溶液法合成了2个新的双核铜配合物：[Cu2(CH3COO)4(L1)2](1)和[Cu2(CH3COO)4(L2)2](2)，并利用熔点、红外光谱、紫外可见光谱、荧光光谱、高分辨质谱和X射线单晶衍射等手段对其进行表征。1属于正交晶系Pbca空间群； 2属于单斜晶系P21/n空间群。每个配合物含有2个铜中心离子、4个醋酸根离子和2个配体(L1或L2)分子；每个醋酸根都起到桥联作用，分别与2个Cu2+配位，形成笼状结构；每个Cu2+均为五配位变形四方锥构型。1和2对金黄色葡萄球菌、枯草芽孢杆菌、大肠杆菌显示出良好抑制作用；对DPPH·具有良好清除效果；均表现出准可逆氧化还原的电化学特性。 | |
| 关键词: 双核铜(Ⅱ)配合物 氨基吡啶 晶体结构 电化学性质 生物活性 | |
| 基金项目: 江苏省高等学校自然科学研究重大项目(No.19KJA430008)、江苏省研究生科研与实践创新计划项目(No.SJCX20-1226,KYCX20-2946)、大学生实践创新训练计划项目(No.X202011641319002,X202011641640002,Z202111641640001,Z202111641640016,Z202111641640017)资助。 | |
| Abstract: 3-Methyl-2-aminopyridine (L1) and 5-bromo-2-aminopyridine (L2) were used as ligands respectively, and two novel binuclear copper(Ⅱ) complexes,[Cu2(CH3COO)4(L1)2] (1) and[Cu2(CH3COO)4(L2)2] (2), have been synthesized by the reaction of the above-mentioned ligands with anhydrous cupric acetate in ethanol solution. The two copper(Ⅱ)complexes were characterized by the methods of melting point, FT -IR, UV -Vis, fluorescence spectra, and HRMS. The crystal structures of 1 and 2 were analyzed by single-crystal X-ray diffraction, which indicates that 1 crystallizes in the orthorhombic system with Pbca space group, while 2 crystallizes in the monoclinic system with P21/n space group. Each of the two binuclear Cu(Ⅱ) complexes contains two copper center cations, four acetate ions, and two L1 or L2 ligands. Each acetate acts as a bridging ligand and coordinates to two Cu(Ⅱ) cations forming a cagelike structure. Each Cu(Ⅱ) cation in complexes 1or 2 is pentacoordinate to one N atom in one pyridine ring and four O atoms in four acetate ions, and the geometries around Cu(Ⅱ) in 1 or 2 are distorted square pyramid. The antibacterial activities of 1 and 2 were investigated by the agar diffusion method, and the result indicated that 1 and 2 had good antibacterial inhibiting effects against Staphylococcus aureus, Bacillus subtilis, and Escherichia coli. And their antioxidant activities were valued using the 2,2-diphenyl-1-picrylhydrazyl (DPPH·) method, which showed that both of them possessed good scavenging capability on DPPH·. Moreover, the electrochemical properties of 1 and 2 were studied by the cyclic voltammetry method, and the results indicate that 1 and 2 showed quasi-reversible redox processes. | |
| Keywords: binuclear copper(Ⅱ) complexes amino pyridines crystal structure electrochemical property bioactivity | |
| 投稿时间：2022-01-21 修订日期：2022-04-16 | |
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| 佟萍,吴江萌,徐萍,王晓莹,李海南,王城,杨斯淇,周嘉荟,许瑞波.2-氨基吡啶类双核铜(Ⅱ)配合物的合成、晶体结构及性质[J].无机化学学报,2022,38(7):1309-1316. | |
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