| 硫酸铈对5′-腺嘌呤及5′-鸟嘌呤核苷酸的水解断裂的催化作用 | |
| CATALYSIS OF HYDROL YTIC CLEAVAGE OF ADENOSINE-5′-MONOPHOSPHATE AND GUANOSINE-5′-MONOPHOSPHATE BY CERIC SULFATE | |
| 摘要: 本文用核磁共振(NMR)波谱和化学定磷法研究了Ce(SO4)2对5′-腺嘌呤核苷酸(5′-AMP)及5′-鸟嘌呤核苷酸(5′-GMP)的水解断裂作用。结果表明:Ce(SO4)2在37℃,酸性条件下使5′-AMP断裂为腺嘌呤核苷(A)及无机磷,使5′-GMP断裂为鸟嘌呤核苷(G)及无机磷,SO42-浓度及酸强度对5′-AMP及5′-GMP的水解断裂程度有很大影响,并对其水解断裂机制进行了研究。 | |
| 关键词: 硫酸铈 5′-腺嘌呤及5′-鸟嘌呤核苷酸 水解断裂作用 | |
| 基金项目: 国家攀登计划“希土科学基础研究”项目;中国科学院基础局资助项目 | |
| Abstract: In this paper,the hydrolysis of adenosine-5′-monophosphate(5′-AMP) and guanosine5′monophosphate(5′-GMP) by Ce(SO4)2 was investigated by NMR and the method of measuring the liberated inorganic phosphate. The results showed that 5′-AMP was converted to adenosine(A) and phosphate and5′GMP was converted to guanosine(G) and phosphate by Ce(SO4)2 at 37℃ under acidic conditions. The concentration of SO42- and acid strength greatly influenced the degree of hydrolysis of 5′-AMP and 5′-GMP. The mechanism of hydrolytic of cleavage was discussed in detail. | |
| Keywords: ceric sulfate adenosine- 5′- monophosphate guanosine- 5′-monophosphate hydrolytic cleavage | |
| 投稿时间：1995-04-24 | |
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| 朱兵,李新民,吴亦洁,赵大庆,倪嘉缵.硫酸铈对5′-腺嘌呤及5′-鸟嘌呤核苷酸的水解断裂的催化作用[J].无机化学学报,1996,12(1):1-6. | |
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