| 过渡金属配合物断裂双链DNA及其机理 |
| Progress on the Mechanisms for Double-Stranded DNA Scission Mediated by Transition Metal Complexes |
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| 摘要: 本文讨论了过渡金属配合物导致DNA双链断裂的各种攫氢反应及碱基氧化机理,对由水解过程促进DNA断裂的过渡金属配合物也作了介绍。 |
| 关键词: DNA 过渡金属配合物 攫氢 碱基氧化 水解 |
| 基金项目: 国家自然科学青年基金(No.29871011);湖北自然科学资助(mo.987051) |
| Abstract: Transition metal complex-mediated double-stranded DNA scission via hydrogen abstraction from the sugar moiety and base oxidation is reviewed.DNA hydrolytic cleavage promoted by transition metal complexes is also discussed in detail. |
| Keywords: DNA transition metal complex hydrogen abstraction base oxidation hydrolytic cleavage |
| 投稿时间：1999-07-14 修订日期：1999-10-21 |
| 摘要点击次数: 1293 |
| 全文下载次数: 1451 |
| 刘长林,余四旺,徐辉碧,周井炎.过渡金属配合物断裂双链DNA及其机理[J].无机化学学报,2000,16(3):374-384. |
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