| 混胺二元羧酸根合铂(Ⅱ)混配配合物的合成及其抗肿瘤活性 |
| Synthesis, Characterization and Antitumor Activities of Platinum(Ⅱ) Complexes of Ammine/Amine with Bidentate Carboxylate |
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| 摘要: |
| 关键词: 混胺铂配合物 合成 抗肿瘤活性 |
| 基金项目: 浙江省自然科学基金(No.298068) |
| Abstract: Complexes of the type [Pt(Ⅱ)(CH3NH2)(NH3){(OOC)2(CH2)n}](Ⅰ～Ⅲ )(n=0,1,2) have been synthesized for the first time. At the same time, the three precursor complexes also have been synthesized. They were characterized by elemental analyses, molar conductance, differential thermal analyses and spectral (IR, UV, 1H NMR) studies. In vitro antitumor activity results indicated that these complexes have activity against HL-60 and U937, but show poor activity against K562. |
| Keywords: mixed amine platinum complexes synthesis antitumor activity |
| 投稿时间：1999-10-08 修订日期：1999-11-15 |
| 摘要点击次数: 1065 |
| 全文下载次数: 1534 |
| 张金超,龚钰秋,郑小明.混胺二元羧酸根合铂(Ⅱ)混配配合物的合成及其抗肿瘤活性[J].无机化学学报,2000,16(4):665-668. |
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