| 三苯基锡壳聚糖黄原酸酯的合成、表征及其杀螺活性研究 |
| Synthesis, Characterization and Molluscicidal Activity of Triphenyltin Chitosan Xanthogenate |
| 作者 | 单位 | E-mail | | 曹佐英 | 湖南理工学院化学化工系, 岳阳, 414000 | | | 许海峰 | 湖南理工学院化学化工系, 岳阳, 414000
中南大学化学化工学院, 长沙, 410083 | xuhaifeng0425@126.com | | 唐瑞仁 | 中南大学化学化工学院, 长沙, 410083 | | | 魏望远 | 湖南省血吸虫病防治所, 岳阳, 414000 | | | 许外 | 湖南理工学院化学化工系, 岳阳, 414000 | |
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| 摘要: 壳聚糖(chitosan,简称CTS)是由β(1～4)键合的D-葡糖胺残基和数目不同排列无规的N-乙酰基葡糖胺残基组成的线性多糖,是生物界中大量存在的唯一的一种碱性多糖.由于壳聚糖具有良好的生物相容性、生物可降解性和抗菌性,所以在医药、食品、化妆品、环保及生物医用材料等领域有着很好的应用前景[1～4]. |
| 关键词: 三苯基锡 壳聚糖黄原酸酯 合成 表征 杀钉螺活性 |
| 基金项目: 湖南省自然科学基金资助项目(No.06JJ20003) |
| Abstract: Dithiocarbamate-modified chitosan(chitosan xanthogenate,DTC-CTS) was synthesized by reaction of chitosan with CS2 in the presence of NaOH.The substitution degree for DTC-CTS is shown by elemental analysis to be 0.74.Triphenyltin chitosan xanthogenate(DTC-CTS-SnPh3),(Ph3SnS2CNHC6H9O4)n,were further prepared by the nucleophilic substitution reaction of chitosan xanthogenate with triphenyltin chloride in the presence of anhydrous methanol.These compounds were characterized by UV,IR,TG-DTA and X-ray diffraction methods etc.The experiments of molluscicidal activity show that the oncomelania death rate is 100% when the concentration of the DTC-CTS-SnPh3 reaches above 0.5000 mg·L-1 and the soaking time is 72 h. |
| Keywords: triphenyltin chitosan xanthogenate synthesis characterization molluscicidal activity |
| 投稿时间：2007-10-10 修订日期：2007-12-20 |
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| 曹佐英,许海峰,唐瑞仁,魏望远,许外.三苯基锡壳聚糖黄原酸酯的合成、表征及其杀螺活性研究[J].无机化学学报,2008,24(3):474-478. |
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